Nociceptive Neurons Induced By Neonatal Capsaicin Treatment in Trigeminal NMDA Receptor Involvement in Neuroplastic Changes

نویسندگان

  • Chen Yu Chiang
  • James W. Hu
  • Barry J. Sessle
  • CHEN YU CHIANG
  • JAMES W. HU
  • BARRY J. SESSLE
  • Chen Yu
چکیده

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NMDA receptor involvement in neuroplastic changes induced by neonatal capsaicin treatment in trigeminal nociceptive neurons.

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RAPID COMMUNICATION NMDA Receptor Involvement in Neuroplastic Changes Induced By Neonatal Capsaicin Treatment in Trigeminal Nociceptive Neurons

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Effects of GABA receptor antagonist on trigeminal caudalis nociceptive neurons in normal and neonatally capsaicin-treated rats.

We have recently demonstrated that significant increases in cutaneous mechanoreceptive field (RF) size and spontaneous activity occur in nociceptive neurons of trigeminal subnucleus caudalis (Vc, the medullary dorsal horn) of adult rats depleted of C-fiber afferents by neonatal treatment with capsaicin. These neuronal changes in capsaicin-treated (CAP) rats are suggestive of central neuroplasti...

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تاریخ انتشار 1997